Detailed monitoring of a rock glacier spring in the Eastern Alps showed that more than 1 tonne of toxic solutes, such as aluminum, nickel, and manganese, is mobilized each year from a small permafrost area. The strong mobilization is caused by rock weathering and long-term accumulation of toxic solutes in permafrost ice. Today, climate-change-induced permafrost degradation leads to a quick and focused export in summer. This forms an unexpected, novel hazard for alpine and high-latitude areas.